What is Consonance Testing?
What is Consonance Testing?
Consonance Testing is a concept in statistical hypothesis testing that ensures logical consistency within a family of hypotheses. Statistical hypothesis testing is a method used in statistics to make decisions or inferences about a population based on a sample of data. It helps determine whether there is enough evidence in a sample of data to support or reject a specific claim (called a hypothesis) about a population.
π What is Consonance Testing?
In statistical hypothesis testing, consonance refers to a property of multiple testing procedures, especially within closed testing frameworks, where:
If a composite hypothesis is not rejected, then none of its sub-hypotheses should be rejected.
This means consonance testing ensures that test results are logically consistent β you cannot reject a more specific hypothesis while accepting a broader one that includes it.
π§ Example Scenario:
Consider testing the following hypotheses:
- H0: No treatment effect in any subgroups.
- H01: No treatment effect in men.
- H02: No treatment effect in women.
A consonant test ensures that if you do not reject H0, then you also do not reject H01 or H02. Rejecting a sub-hypothesis while accepting the full hypothesis would be inconsistent.
β Importance of Consonance Testing
- Prevents illogical conclusions.
- Used in closed testing procedures like Bonferroni or Holm corrections.
- Helps maintain control over family-wise error rate (FWER).
π§ Where Is It Used?
- Multiple testing frameworks
- Clinical trials (group and subgroup testing)
- Genomics (gene and pathway testing)
- Statistical software for multiple comparisons